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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2630 | Poziotinib | HM781-36B,NOV120101 | Apoptosis , EGFR , HER |
Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM). | |||
T8758 | Poziotinib hydrochloride | HM 781-36B hydrochloride,NOV120101 hydrochloride | EGFR |
Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavaila... |